Search results for " amalgam"
showing 10 items of 20 documents
Differential metallothionein expression in oral lichen planus and amalgam-associated oral lichenoid lesions
2017
Background Oral lichen planus (OLP) is a chronic inflammatory disease mediated by T cells, which manifests as reticular (white) or erosive (red) lesions, that are eventually painful. Oral lichenoid lesion (OLL) are distinguished from OLP by the presence of precipitating factors. The aim of this study was to evaluate whether the presence of metallothionein, which is involved in anti-apoptotic pathways and the anti-oxidative response, could serve as a differential diagnostic for OLP and OLL. Material and Methods We evaluated the expression of metallothionein in 40 cases of OLP and 20 cases of OLL using immunohistochemistry. Results and Conclusions White OLP has higher concentrations of metall…
Oral lichenoid lesions associated with amalgam restorations : a prospective pilot study addressing the adult population of the Basque Country
2011
Oral lichenoid lesions (OLLs) are linked to a heterogeneous group of pathologies involving the oral mucosa that cannot be distinguished from the oral lichen planus excepting the fact that direct causal factors such as silver amalgam restorations (SARs) can be allocated to them. Purpose: To analyze the prevalence of mucosal lesions associated with SAR in a group of SAR carrying patients in the Basque Country. Study D esign: A clinical prospective study was carried out on 100 adult patients over 30 years of age at the UPV/ EHU Clinical Odontology Service whose rear teeth had at least one SAR. Patients were identified and mucosal lesions and amalgam restorations were characterized. Patch tests…
A comparative study of silver amalgam and compomer as retrograde filling materials in periapical surgery
2008
Objective: A comparative study is made of the histological effects of silver amalgam versus compomer (Dyract®) 90 days after placement as retrograde filling materials in experimental animals. Method: Six Beagle dogs were used, with total pulpectomy and orthograde material filling followed by periapical surgery of the 6 upper and 6 lower incisors (for a total of 72 teeth). Thirty-six teeth corresponded to the right side and were filled with the control material (silver amalgam), while the 36 teeth on the left side were filled with the compomer study material (Dyract®). After three months the animals were sacrificed and the histological study was carried out, with evaluation of bone formation…
Two-carbon bridge substituted cocaines: enantioselective synthesis, attribution of the absolute configuration and biological activity of novel 6- and…
1999
In an effort to learn more about the general structure-activity relationships of cocaine with the aim to elucidate those structural features that might confer antagonistic properties to such analogues, we describe herein our synthetic efforts to prepare two-carbon bridge functionalized (methoxylated and hydroxylated) analogues. Our approach makes use of a modification of the classical Willstatter synthesis of cocaine: Mannich type cyclization of acetonedicarboxylic acid monomethyl ester with methylamine hydrochloride and 2-methoxysuccindialdehyde in a citrate buffer solution afforded the 6- and 7-substituted 2-carbomethoxy-3-tropinones 3a,b and 4a,b in approximate yields of 64%. Reduction o…
Clinical and radiological course in apicoectomies with the Erbium : YAG LASER
2007
A study is made of the efficacy of the Erbium: YAG laser in granulomatous periapical lesions, based on clinical and radiographic controls. The study comprised a series of 45 patients amenable to periapical surgical treatment of incisors, canines and premolars. A conventional surgical technique was used, with silver amalgam retrograde filling and irradiation of the bone defect and remnant root cement with the Erbium: YAG laser. Clinical and radiographic controls were made during 24 months, assessing the absence of symptoms and the presence of pain, swelling or fistula and ossification of the lesions, respectively. The clinical course proved asymptomatic in 95.5% of the cases. As regards remo…
Sealing ability of five different retrograde filling materials.
1996
The sealing ability of Amalgam, Harvard-Cement, Diaket, gold-leaf, and Ketac-Endo as retrofilling materials was investigated. Paper cones were fixed with Harvard-Cement in the instrumented roots of 100 extracted human incisors. Apicectomy was performed and a 2-mm-deep retrograde cavity was prepared. Teeth were assigned to five groups (n = 20); each group received a different filling material. Surfaces of the roots were isolated with nail polish. Teeth, were stored in 1% methylene blue dye for 72 h. Roots were sectioned, and the depth of dye penetration was evaluated through a stereomicroscope. Retrofills with Ketac-Endo showed significantly less leakage compared with amalgam. There was no s…
Comparison of different uncertainty techniques in urban stormwater quantity and quality modelling
2011
Abstract Urban drainage models are important tools used by both practitioners and scientists in the field of stormwater management. These models are often conceptual and usually require calibration using local datasets. The quantification of the uncertainty associated with the models is a must, although it is rarely practiced. The International Working Group on Data and Models, which works under the IWA/IAHR Joint Committee on Urban Drainage, has been working on the development of a framework for defining and assessing uncertainties in the field of urban drainage modelling. A part of that work is the assessment and comparison of different techniques generally used in the uncertainty assessm…
Lexical classes and constructions: an analysis of the constructional realization of entity-specific change-of-state English verbs
2013
This study analyzes a so far neglected part of the constructional behavior of Levin's (1993) entity-specific change-of-state verbs. More specifically, we discuss the integration of verbs from this lexical class into the intransitive-resultative construction. We base our analysis on the Lexical Constructional Model or LCM (Ruiz de Mendoza and Mairal 2008, 2011; Mairal and Ruiz de Mendoza 2009; Ruiz de Mendoza 2013). It will be shown that the internal and external constraints postulated by the LCM constitute useful explanatory and analytical tools for the fusion processes between these verbs and the intransitive-resultative construction. We also propose a classification of these verbs on the …
Clinicopathological and Immunohistochemical Study of Oral Amalgam Pigmentation
2012
Amalgam tattoo, the most common exogenous oral pigmentation, can sometimes be confused with melanotic lesions, being then biopsied. We present the clinicopathological characteristics of 6 biopsied cases (5 females and 1 male) of oral amalgam pigmentation. The most common location was the gingival mucosa, followed by the buccal and palatal mucosa. Morphology and distribution (stromal, perivascular, perineural, endomysial) of pigmentation was variable; there was only 1 case with fibrous capsular reaction and likewise only a single case of granulomatous foreign body reaction. Morphological variability is conditioned by the timing and amount of the pigment deposit, which is often associated wit…
Amalgam fillings and cognitive abilities in a representative sample of the elderly population.
2000
Objectives: The ongoing controversial discussion about a possible negative effect of amalgam fillings on the cognitive abilities and the pathogenesis dementia was the objective of the present study. Sample: A total of 300 patients aged from 70 to 103 years were selected from the multidisciplinary ‘Berlin Aging Study’ (Base). The sample was heterogeneous concerning lifestyle, education and social prestige. According to their dental state subjects were allocated into three groups: edentate ≥20 years (I) and residual teeth without (II) or with (III) amalgam restorations. All groups were matched for age and gender. Design: Dental examinations and various psychiatric as well as psychological ass…